Nitroxinil Injection 34% (veterinary medicine)

Nitroxinil Injection 34%   is indicated for the treatment of fascioliasis (infestations of mature and

 immature Fasciola hepatica) in cattle and sheep. Nitroxinil Injection 34% Cattle is also effective, 

at the recommended dose rate, against adult and larval infestations of Haemonchus contortus in 

cattle and sheep and Haemonchus placei, Oesophagostomum radiatum and Bunostomum 

phlebotomum in cattle.Nitroxinil Injection 34% Sheep.

Nitroxinil 34% injectable solution

Aqueous solution for parenteral use.

Description

The main pharmacological action of the active ingredient in Fluconix-340, nitroxinil, is fasciolicidal.

The lethal action against Fasciola hepatica has been demonstrated in vitro and in vivo in laboratory 

animals, and in sheep and cattle. The mechanism of action is due to uncoupling of oxidative 

phosphorylation. It is also active against triclabendazole-resistant 
F. hepatica. 

Composition

Indications

Nitroxinil 34% injectable  is indicated for the treatment of fascioliasis (infestations of mature and

immature Fasciola hepatica) in cattle and sheep. It is also effective, at the recommended dose

rate, against adult and larval infestations of Haemonchus contortus in cattle and sheep and 

Haemonchus placei, Oesophagostomum radiatum and Bunostomum phlebotomum in cattle.

Contra indications

Do not use in animals with known hypersensitivity to the active ingredient. 
Do not use in animals producing milk for human consumption. 
Do not exceed stated dose. 

Side effects

Small swellings are occasionally observed at the injection site in cattle. These can be avoided by

 injecting the dose in two separate sites and massaging well to disperse the solution. No systemic

 ill effects are to be expected when animals (including pregnant cows and ewes) are treated at 

normal dosage.

Dosage

Administer by subcutaneous injection: 
The standard dosage is 10 mg nitroxinil per kg body weight. 
Sheep: Administer according to the following doses scale: 

41 - 55 kg : 1.5 ml
56 - 75 kg : 2.0 ml
 > 75 kg   : 2.5 ml

Withdrawal times
In outbreaks of fascioliasis each sheep in the flock should be injected immediately when the

 presence of the disease is recognised, repeating treatment as necessary throughout the period 

when infestation is occurring, at intervals of not less than one month. 
Cattle: 1.5 ml of this product per 50 kg of bodyweight. 
Both infected and in-contact animals should be treated, treatment being repeated as considered 

necessary, though not more frequently than once per month. Dairy cows should be treated at 

drying off (at least 28 days before calving). 

Note:

 Do not use in animals producing milk for human consumption.

-For meat: 
Cattle: 60 days. 
Sheep: 49 days. 

Warning

Keep out of reach of children.

Packing

Vials of 50 and 100 ml.